Activities

The identification, isolation and characterization of allergens is crucial for diagnosis and therapy of allergic disorders. The team focuses on the analysis of respiratory and food allergens from animal origin. A large panel of characterized fish and furry pet allergens became available during the past decade.

The use of single allergens in IgE-diagnosis allows to discriminate between a primary sensitization and cross-reactivity, a first step into personalized diagnosis and treatment. We are closely linked to the clinic through our partner, the National Service of Immuno-Allergology at CHL. The analysis of common allergen features helps to understand the allergic immune response and as a perspective, to develop strategies for patient immunotherapy.

Research projects

  • Analysis of respiratory allergens from small furry animals
  • Analysis of food allergens from fish and meat
  • Developing strategies for improved patient diagnosis, care and treatment

Featured Publications

Atopic dermatitis patients with pet dander sensitization mount IgE and T cell responses to mammalian cystatins including the human self-protein.

  • Molecular and Translational Allergology
  • Allergy and Clinical Immunology
September 03, 2021
2021 Sep. J Investig Allergol Clin Immunol. Online ahead of print.
By:
  • Roesner LM
  • Swiontek K
  • Lentz D
  • Begemann G
  • Kienlin P
  • Hentges F
  • Ollert M
  • Werfel T
  • Hilger C.

Characterization of new allergens from the venom of the European paper Wasp Polistes dominula.

  • Molecular and Translational Allergology
  • Allergy and Clinical Immunology
August 10, 2021
2021 Aug. Toxins.13(8).
By:
  • Grosch J
  • Eberlein B
  • Waldherr S
  • Pascal M
  • San Bartolome C
  • De La Roca Pinzon F
  • Dittmar M
  • Hilger C
  • Ollert M
  • Biedermann T
  • Darsow U
  • Bilo MB
  • Schmidt-Weber CB
  • Blank S.
See all publications

Contacts

Christiane Hilger

Ph.D.

29, rue Henri Koch
L-4354Esch-sur-Alzette
Luxembourg
Tel. : +352 26970-258

Annette KUEHN

PhD

29, rue Henri Koch
L-4354 Esch-Sur-Alzette
LUXEMBOURG
Tel. : +352 26 970 335