Simone Niclou

Latest publications

Multimodal imaging of gliomas in the context of evolving cellular and molecular therapies.

  • NORLUX Neuro-Oncology Laboratory
September 30, 2014
2014 Sep. Adv Drug Deliv Rev.76:98-115. Epub 2014 Jul 28.
By:
  • Keunen O
  • Taxt T
  • Gruner R
  • Lund-Johansen M
  • Tonn JC
  • Pavlin T
  • Bjerkvig R
  • Niclou SP
  • Thorsen F.

PeptideManager: a peptide selection tool for targeted proteomic studies involving mixed samples from different species.

  • NORLUX Neuro-Oncology Laboratory
  • Proteomics of Cellular Signaling
September 02, 2014
2014 Sep. Front Genet.5:305.
By:
  • Demeure K
  • Duriez E
  • Domon B
  • Niclou SP.

Factors influencing the mechanical stability of alginate beads applicable for immunoisolation of mammalian cells.

  • NORLUX Neuro-Oncology Laboratory
September 01, 2014
2014 Sep. J Mech Behav Biomed Mater.37:196-208. Epub 2014 Jun 2.
By:
  • Bhujbal SV
  • Paredes-Juarez GA
  • Niclou SP
  • de Vos P.

Glutamate as chemotactic fuel for diffuse glioma cells: are they glutamate suckers?

  • NORLUX Neuro-Oncology Laboratory
August 01, 2014
2014 Aug. Biochim Biophys Acta-Rev Cancer 1846(1):66-74. Epub 2014 Apr 18.
By:
  • van Lith SA
  • Navis AC
  • Verrijp K
  • Niclou SP
  • Bjerkvig R
  • Wesseling P
  • Tops B
  • Molenaar R
  • van Noorden CJ
  • Leenders WP.

Colorectal cancer derived organotypic spheroids maintain essential tissue characteristics but adapt their metabolism in culture.

  • NORLUX Neuro-Oncology Laboratory
July 11, 2014
2014 Jul. Proteome Sci.12:39.
By:
  • Rajcevic U
  • Knol JC
  • Piersma S
  • Bougnaud S
  • Fack F
  • Sundlisaeter E
  • Sondenaa K
  • Myklebust R
  • Pham TV
  • Niclou SP
  • Jimenez CR.

U-251 revisited: genetic drift and phenotypic consequences of long-term cultures of glioblastoma cells.

  • NORLUX Neuro-Oncology Laboratory
May 08, 2014
2014 May. Cancer Med.3(4):812-24. Epub 2014 May 8.
By:
  • Torsvik A
  • Stieber D
  • Enger PO
  • Golebiewska A
  • Molven A
  • Svendsen A
  • Westermark B
  • Niclou SP
  • Olsen TK
  • Chekenya Enger M
  • Bjerkvig R.

Bevacizumab treatment for human glioblastoma. Can it induce cognitive impairment?

  • NORLUX Neuro-Oncology Laboratory
May 01, 2014
2014 May. Neuro Oncol.16(5):754-6.
By:
  • Pakzad A
  • Obad N
  • Espedal H
  • Stieber D
  • Keunen O
  • Sakariassen PO
  • Niclou SP
  • Bjerkvig R.

Drug and cell encapsulation: alternative delivery options for the treatment of malignant brain tumors.

  • NORLUX Neuro-Oncology Laboratory
April 10, 2014
2014 Apr. Adv Drug Deliv Rev.67-68:142-53. Epub 2014 Jan 31.
By:
  • Bhujbal SV
  • de Vos P
  • Niclou SP.

Glioblastomas are composed of genetically divergent clones with distinct tumourigenic potential and variable stem cell-associated phenotypes.

  • NORLUX Neuro-Oncology Laboratory
  • Platform National Cytometry
  • Platform LUXGEN - Micro-Array
February 01, 2014
2014 Feb. Acta Neuropathol.127(2):203-1. Epub 2013 Oct 24.
By:
  • Stieber D
  • Golebiewska A
  • Evers L
  • Lenkiewicz E
  • Brons NH
  • Nicot N
  • Oudin A
  • Bougnaud S
  • Hertel F
  • Bjerkvig R
  • Vallar L
  • Barrett MT
  • Niclou SP.

Tumor versus stromal cells in culture--survival of the fittest?

  • NORLUX Neuro-Oncology Laboratory
December 02, 2013
2013 Dec. PLoS One.8(12):e81183.
By:
  • Talasila KM
  • Brekka N
  • Mangseth K
  • Stieber D
  • Evensen L
  • Rosland GV
  • Torsvik A
  • Wagner M
  • Niclou SP
  • Mahesparan R
  • Vintermyr OK
  • Bjerkvig R
  • Nigro JM
  • Miletic H.

Granzyme B degradation by autophagy decreases tumor cell susceptibility to natural killer-mediated lysis under hypoxia.

  • Tumor Immunotherapy and Microenvironment
  • NORLUX Neuro-Oncology Laboratory
October 22, 2013
2013 Oct. Proc Natl Acad Sci U S A.110(43):17450-5. Epub 2013 Oct 7.
By:
  • Baginska J
  • Viry E
  • Berchem G
  • Poli A
  • Noman MZ
  • van Moer K
  • Medves S
  • Zimmer J
  • Oudin A
  • Niclou SP
  • Bleackley RC
  • Goping IS
  • Chouaib S
  • Janji B.

The soluble form of the tumor suppressor Lrig1 potently inhibits in vivo glioma growth irrespective of EGF receptor status.

  • NORLUX Neuro-Oncology Laboratory
September 01, 2013
2013 Sep. Neuro Oncol.15(9):1200-11. Epub 2013 May 30.
By:
  • Johansson M
  • Oudin A
  • Tiemann K
  • Bernard A
  • Golebiewska A
  • Keunen O
  • Fack F
  • Stieber D
  • Wang B
  • Hedman H
  • Niclou SP.

Gene set based integrated data analysis reveals phenotypic differences in a brain cancer model.

  • NORLUX Neuro-Oncology Laboratory
July 09, 2013
2013 Jul. PLoS One.8(7):e68288.
By:
  • Petersen K
  • Rajcevic U
  • Abdul Rahim SA
  • Jonassen I
  • Kalland KH
  • Jimenez CR
  • Bjerkvig R
  • Niclou SP.

Combined effect of tissue stabilization and protein extraction methods on phosphoprotein analysis.

  • Integrated BioBank of Luxembourg
  • NORLUX Neuro-Oncology Laboratory
June 01, 2013
2013 Jun. Biopreserv Biobank.11(3):161-5.
By:
  • Kofanova OA
  • Fack F
  • Niclou SP
  • Betsou F.

In vivo animal models for studying brain metastasis: value and limitations.

  • NORLUX Neuro-Oncology Laboratory
June 01, 2013
2013 Jun. Clin Exp Metastasis.30(5):695-710. Epub 2013 Jan 16.
By:
  • Daphu I
  • Sundstrom T
  • Horn S
  • Huszthy PC
  • Niclou SP
  • Sakariassen PO
  • Immervoll H
  • Miletic H
  • Bjerkvig R
  • Thorsen F.

Increased mitochondrial activity in a novel IDH1-R132H mutant human oligodendroglioma xenograft model: in situ detection of 2-HG and α-KG.

  • NORLUX Neuro-Oncology Laboratory
May 29, 2013
2013 May. Acta Neuropathol Commun.1:18.
By:
  • Navis AC
  • Niclou SP
  • Fack F
  • Stieber D
  • van Lith S
  • Verrijp K
  • Wright A
  • Stauber J
  • Tops B
  • Otte-Holler I.

Side population in human glioblastoma is non-tumorigenic and characterizes brain endothelial cells.

  • NORLUX Neuro-Oncology Laboratory
  • Platform National Cytometry
  • Platform LUXGEN - Micro-Array
May 01, 2013
2013 May. Brain.136(Pt 5):1462-75. Epub 2013 Mar 4.
By:
  • Golebiewska A
  • Bougnaud S
  • Stieber D
  • Brons NH
  • Vallar L
  • Hertel F
  • Klink B
  • Schrock E
  • Bjerkvig R
  • Niclou SP.

EGFR wild-type amplification and activation promote invasion and development of glioblastoma independent of angiogenesis.

  • NORLUX Neuro-Oncology Laboratory
May 01, 2013
2013 May. Acta Neuropathol.125(5):683-98. Epub 2013 Feb 22.
By:
  • Talasila KM
  • Soentgerath A
  • Euskirchen P
  • Rosland GV
  • Wang J
  • Huszthy PC
  • Prestegarden L
  • Skaftnesmo KO
  • Sakariassen PO
  • Eskilsson E
  • Stieber D
  • Keunen O
  • Brekka N
  • Moen I
  • Nigro JM
  • Vintermyr OK
  • Lund-Johansen M
  • Niclou S
  • Mork SJ
  • Enger PO
  • Bjerkvig R
  • Miletic H.

A novel, diffusely infiltrative xenograft model of human anaplastic oligodendroglioma with mutations in FUBP1, CIC, and IDH1.

  • NORLUX Neuro-Oncology Laboratory
March 26, 2013
2013 Mar. PLoS One.8(3):e59773. Epub 2013 Mar 19.
By:
  • Klink B
  • Miletic H
  • Stieber D
  • Huszthy PC
  • Campos Valenzuela JA
  • Balss J
  • Wang J
  • Schubert M
  • Sakariassen PO
  • Sundstrom T
  • Torsvik A
  • Aarhus M
  • Mahesparan R
  • von Deimling A
  • Kaderali L
  • Niclou SP
  • Schrock E
  • Bjerkvig R
  • Nigro JM.

Animal models for low-grade gliomas. In Diffuse Low-Grade Gliomas in Adults. 1st ed. (Book Chapter)

  • NORLUX Neuro-Oncology Laboratory
March 11, 2013
2013 Mar. Duffau H, ed. Berlin: Springer, 2013. p.165-175. ISBN 978-1-4471-2212-8.
By:
  • Bjerkvig R
  • Bougnaud S
  • Niclou SP.