Dirk Brenner

Latest publications

TNF and ROS crosstalk in inflammation.

  • Experimental and Molecular Immunology
April 01, 2016
2016 Apr. Trends Cell Biol.26(4):249-61. Epub 2016 Jan 12.
By:
  • Blaser H
  • Dostert C
  • Mak TW
  • Brenner D.

Idh1 protects murine hepatocytes from endotoxin-induced oxidative stress by regulating the intracellular NADP(+)/NADPH ratio.

  • Experimental and Molecular Immunology
November 01, 2015
2015 Nov. Cell Death Differ.22(11):1837-45. Epub 2015 Apr 17.
By:
  • Itsumi M
  • Inoue S
  • Elia AJ
  • Murakami K
  • Sasaki M
  • Lind EF
  • Brenner D
  • Harris IS
  • Chio
  • II
  • Afzal S
  • Cairns RA
  • Cescon DW
  • Elford AR
  • Ye J
  • Lang PA
  • Li WY
  • Wakeham A
  • Duncan GS
  • Haight J
  • You-Ten A
  • Snow B
  • Yamamoto K
  • Ohashi PS
  • Mak TW.

Antigen receptor-mediated depletion of FOXP3 in induced regulatory T-lymphocytes via PTPN2 and FOXO1.

  • Experimental and Molecular Immunology
October 13, 2015
2015 Oct. Nat Commun.6:8576.
By:
  • Bothur E
  • Raifer H
  • Haftmann C
  • Stittrich AB
  • Brustle A
  • Brenner D
  • Bollig N
  • Bieringer M
  • Kang CH
  • Reinhard K
  • Camara B
  • Huber M
  • Visekruna A
  • Steinhoff U
  • Repenning A
  • Bauer UM
  • Sexl V
  • Radbruch A
  • Sparwasser T
  • Mashreghi MF
  • Wah Mak T
  • Lohoff M.

Regulation of tumour necrosis factor signalling: live or let die.

  • Experimental and Molecular Immunology
May 26, 2015
2015 May. Nat Rev Immunol.15(6):362-74.
By:
  • Brenner D
  • Blaser H
  • Mak TW.

Deficiency of MALT1 paracaspase activity results in unbalanced regulatory and effector T and B cell responses leading to multiorgan inflammation.

  • Experimental and Molecular Immunology
April 15, 2015
2015 Apr. J Immunol.194(8):3723-34. Epub 2015 Mar 11.
By:
  • Bornancin F
  • Renner F
  • Touil R
  • Sic H
  • Kolb Y
  • Touil-Allaoui I
  • Rush JS
  • Smith PA
  • Bigaud M
  • Junker-Walker U
  • Burkhart C
  • Dawson J
  • Niwa S
  • Katopodis A
  • Nuesslein-Hildesheim B
  • Weckbecker G
  • Zenke G
  • Kinzel B
  • Traggiai E
  • Brenner D
  • Brustle A
  • St Paul M
  • Zamurovic N
  • McCoy KD
  • Rolink A
  • Regnier CH
  • Mak TW
  • Ohashi PS
  • Patel DD
  • Calzascia T.

Glutathione and thioredoxin antioxidant pathways synergize to drive cancer initiation and progression.

  • Experimental and Molecular Immunology
February 09, 2015
2015 Feb. Cancer Cell.27(2):211-22. Epub 2015 Jan 22.
By:
  • Harris IS
  • Treloar AE
  • Inoue S
  • Sasaki M
  • Gorrini C
  • Lee KC
  • Yung KY
  • Brenner D
  • Knobbe-Thomsen CB
  • Cox MA
  • Elia A
  • Berger T
  • Cescon DW
  • Adeoye A
  • Brustle A
  • Molyneux SD
  • Mason JM
  • Li WY
  • Yamamoto K
  • Wakeham A
  • Berman HK
  • Khokha R
  • Done SJ
  • Kavanagh TJ
  • Lam CW
  • Mak TW.

Autophagy-independent functions of UVRAG are essential for peripheral naive T-cell homeostasis.

  • Experimental and Molecular Immunology
January 27, 2015
2015 Jan. Proc Natl Acad Sci U S A.112(4):1119-24. Epub 2015 Jan 12.
By:
  • Afzal S
  • Hao Z
  • Itsumi M
  • Abouelkheer Y
  • Brenner D
  • Gao Y
  • Wakeham A
  • Hong C
  • Li WY
  • Sylvester J
  • Gilani SO
  • Brustle A
  • Haight J
  • You-Ten AJ
  • Lin GH
  • Inoue S
  • Mak TW.